Structure-based design of combinatorial mutagenesis libraries
نویسندگان
چکیده
منابع مشابه
One-bead-one-structure combinatorial libraries.
Combinatorial libraries employing the one-bead-one-compound technique are reviewed. Two distinguishing features characterize this technique. First, each compound is identified with a unique solid support, enabling facile segregation of active compounds. Second, the identity of a compound on a positively reacting bead is elucidated only after its biological relevance is established. Direct metho...
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ژورنال
عنوان ژورنال: Protein Science
سال: 2015
ISSN: 0961-8368
DOI: 10.1002/pro.2642